Our Services
Comprehensive care for all ages. Specializing in hormone replacement, sexual wellness, weight loss, PRP (platelet-rich-plasma), exosomes, walk-in care, medical cannabis cards, and more! Lab services available in clinic.
Bio-Identical Hormone Replacement
What Is Biote (Bio-identical Hormone Replacement)?
Biote is a leading provider of bioidentical hormone replacement therapy (BHRT), offering a personalized approach to help both men and women achieve hormone balance and improve overall quality of life. As we age, hormone levels naturally decline, which can lead to symptoms like fatigue, mood swings, weight gain, low libido, trouble sleeping, and brain fog. Biote uses custom-compounded hormone pellets—derived from natural sources—that are placed just under the skin to deliver consistent, long-term hormone support.
This safe and effective method helps restore optimal hormone levels, supporting physical, emotional, and mental well-being. Backed by decades of research, Biote empowers individuals to take charge of their health with personalized, science-based care.


Scan to order directly from BioTE through Comprehensive Care Clinic with discounted rates
Symptoms of Hormone Imbalance in Women:
Fatigue
Night sweats
Hot flashes
Decreased sex drive
Weight gain
Trouble sleeping
Irritability
Anxiousness
Mood swings
Brain fog
Low mood
Decreased bone mass
Discomfort during intercourse
Symptoms of Hormone Imbalance in Men:
Low sex drive
Fatigue
Loss of muscle mass
Increased body fat (especially around the waist)
Mood changes
Irritability
Elevated blood sugar
Feelings of stress or anxiety
High cholesterol
Decreased muscle mass
*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
Your BioTE Procedure: What to Expect
If you’re new to hormone therapy, here’s a step-by-step guide to your first BioTE procedure:
Initial Consultation
Before treatment, you'll have a consultation with one of our specialists. This includes:A review of your medical history.
A blood panel to assess your hormone levels.
A discussion of your symptoms and goals.
Customized Treatment Plan
Based on your results, we create a personalized hormone therapy plan that’s tailored to your specific needs.The Insertion Procedure
The BioTE pellet insertion is quick, minimally invasive, and performed in our office:Local Anesthesia: We’ll numb the area (typically your upper hip) so you won’t feel pain during the procedure.
Insertion of Pellets: A small incision is made, and tiny pellets (about the size of a grain of rice) are placed just beneath the skin. The pellets are designed to release hormones gradually over time.
Bandage: The incision is closed with a small bandage—no stitches required. The entire procedure typically takes 15-30 minutes.
Post-Procedure Care
You can go home right after the procedure, though we recommend taking it easy for the next 5-7 days. We'll give you aftercare instructions to help ensure the best results.
What to Expect in the Month Following Your BioTE Treatment
As a first-time patient, it’s important to understand what your body will experience during the first month of BioTE hormone therapy.
Week 1:
Mild Discomfort: The insertion site may feel slightly sore, tender, or bruised. This is normal and should subside within a few days.
Activity Restrictions: For the first 5-7 days, avoid strenuous physical activity (e.g., heavy lifting, running, etc.) and soaking in baths, hot tubs, or pools. This will help the area heal and ensure the pellets stay in place.
Bandage Care: Keep the area clean and dry. We will provide you with detailed aftercare instructions to follow.
Weeks 2-4:
Noticeable Improvements: By the end of the second week, many patients begin to experience some positive changes, such as:
Increased energy levels
Improved mood and emotional stability
Better sleep quality
Enhanced mental clarity
Improved libido
Adjustment Period: Some first-time patients may experience mild side effects during the initial weeks, like slight acne, mood swings, or fluid retention. These symptoms are temporary and typically subside as your body adjusts to the hormones.
Follow-Up: At your 4-week follow-up appointment, we’ll check in to assess your progress. This may include a follow-up blood test to ensure your hormone levels are balanced and to adjust the dosage if needed.
What’s Next After the First Month?
Ongoing Benefits: After your first month, most patients experience continued improvement in overall wellness. The pellets will continue to release hormones gradually for 3–6 months, at which point you’ll return for another treatment.
Long-Term Care: Regular follow-ups and lab tests will help us ensure your treatment stays on track, adjusting your dosage as needed for optimal results.
Why Choose BioTE?
If you’re looking for a natural, long-lasting way to restore hormone balance, BioTE offers a unique and effective solution. This method is designed to be convenient, with minimal downtime and results that can last months at a time.


Medical Weight Loss
Are you ready to start your wellness journey? Transform your body with a comprehensive weight loss program. Our weight loss programs are designed to go beyond just shedding pounds—we focus on helping you lose fat while preserving muscle and boosting overall health. Using GLP-1 medications and phentermine, our providers create a personalized regimen tailored to your needs. Throughout your journey, we closely monitor key factors like protein intake, hydration, and muscle mass to ensure safe, effective, and sustainable results. With the right tools and ongoing support, lasting change is absolutely possible. See below for more information on medications our providers offer or schedule a consult today!
Semaglutide
What is Semaglutide?
Semaglutide is a prescription medication originally developed to treat type 2 diabetes. It belongs to a class of drugs called GLP-1 receptor agonists, which help regulate blood sugar and appetite. More recently, semaglutide has been FDA-approved under brand names like Wegovy® for weight loss in adults with obesity or overweight with at least one weight-related condition (such as high blood pressure or high cholesterol).
How Does It Work?
Semaglutide mimics a natural hormone in your body called GLP-1, which helps:
Reduce hunger and cravings
Slow down digestion, helping you feel full longer
Regulate blood sugar levels
When combined with a healthy diet and lifestyle changes, semaglutide can significantly support weight loss and improve metabolic health.
What Is Semaglutide Used For?
Weight management in adults who are obese (BMI ≥30) or overweight (BMI ≥27) with related health conditions
Blood sugar control in adults with type 2 diabetes (under other brand names)
What to Expect During Treatment
At our clinic, semaglutide is part of a medically guided weight loss plan. Our providers will:
Customize your dosage based on your needs
Monitor your progress regularly
Track key health markers, including hydration, protein intake, and muscle mass
Offer lifestyle support with nutrition and activity guidance
You’ll receive full support throughout your journey to help you stay on track and get the best possible results.
Important Patient Information
Dosing starts low and increases gradually to minimize side effects. It's typically given once a week as an injection.
Common side effects may include nausea, constipation, or mild stomach discomfort, which usually improve over time.
Who should avoid semaglutide? Patients with a personal or family history of medullary thyroid cancer or certain endocrine disorders should not use semaglutide. Always consult with your provider before starting.
Is Semaglutide Right for You?
Semaglutide is a powerful tool for weight loss when used alongside healthy lifestyle changes. Our team will help determine if it’s a safe and effective option based on your individual health needs and goals.
Tirzepatide
What is Tirzepatide?
Tirzepatide is a groundbreaking medication used to support weight loss and improve blood sugar control. Originally developed to treat type 2 diabetes, it’s now also FDA-approved (under the brand name Zepbound®) for chronic weight management in adults with obesity or overweight with related health conditions.
Tirzepatide is a dual-action medication, meaning it targets two key hormones—GLP-1 and GIP—that help regulate appetite, blood sugar, and digestion. This dual effect sets it apart from other weight loss medications and can lead to more significant results.
How Does Tirzepatide Work?
Tirzepatide helps with weight loss and metabolic health by:
Reducing hunger and increasing feelings of fullness
Slowing down how quickly food leaves the stomach
Improving insulin sensitivity and lowering blood sugar levels
This combination helps you eat less, feel more satisfied after meals, and lose weight more effectively when paired with healthy habits.
Who Is Tirzepatide For?
Tirzepatide is prescribed for:
Adults with a BMI of 30 or higher (obesity)
Adults with a BMI of 27 or higher (overweight) who also have at least one weight-related health condition (like high blood pressure, high cholesterol, or type 2 diabetes)
What to Expect with Treatment
At our clinic, tirzepatide is used as part of a comprehensive, medically supervised weight loss program. Our providers will:
Start you on a low dose and gradually increase it to reduce side effects
Monitor your weight, blood sugar, muscle mass, and overall wellness
Support your progress with personalized advice on nutrition, hydration, protein intake, and physical activity
Common Side Effects
Most side effects are mild and improve over time. They may include:
Nausea or upset stomach
Diarrhea or constipation
Decreased appetite
Your provider will guide you on how to manage these effects if they occur.
Is Tirzepatide Safe for Everyone?
Tirzepatide is not recommended for people with a personal or family history of medullary thyroid cancer or certain endocrine disorders. A full medical evaluation is required before starting treatment.
Why Choose Tirzepatide?
Tirzepatide offers a powerful, science-backed way to support meaningful weight loss and better health. When combined with personalized support and healthy lifestyle changes, it can be a life-changing tool for long-term success.
Phentermine
What is Phentermine?
Phentermine is an FDA-approved prescription medication used to help with short-term weight loss. It works as an appetite suppressant, helping you feel less hungry and more in control of your eating habits. Phentermine is most effective when used alongside healthy lifestyle changes like balanced nutrition, increased protein intake, exercise, and hydration—under the guidance of a medical provider.
How Does Phentermine Work?
Phentermine is a stimulant that affects the central nervous system. It boosts energy and decreases appetite by increasing levels of certain brain chemicals (norepinephrine), which help reduce hunger and cravings. It’s often used for patients who need an extra push to get started on their weight loss journey.
Who Qualifies for Phentermine?
Phentermine may be appropriate for:
Adults with a BMI of 30 or higher (obesity)
Adults with a BMI of 27 or higher who also have a weight-related health condition, such as:
Type 2 diabetes
High blood pressure
High cholesterol
Before starting, our providers will perform a thorough evaluation to determine if phentermine is safe and appropriate for your health history and goals.
Risks and Considerations
Phentermine is generally safe when used short-term (typically a few weeks to a few months) and under medical supervision. However, because it is a stimulant, it may not be suitable for everyone.
Phentermine may not be right for you if you have:
Heart disease or uncontrolled high blood pressure
Glaucoma
Hyperthyroidism
A history of substance misuse
Are pregnant or breastfeeding
Our team will carefully screen for any health concerns before prescribing phentermine.
Possible Side Effects
Most side effects are mild and improve as your body adjusts to the medication. These may include:
Increased heart rate or blood pressure
Dry mouth
Insomnia or restlessness
Constipation
Dizziness or jitteriness
We monitor your health closely throughout treatment to manage any side effects and adjust the dose or medication plan if needed.
What Patients Should Know
Short-term use only: Phentermine is not intended for long-term use. It’s often used as a jumpstart to help patients adopt healthier habits.
Not a standalone solution: Phentermine works best when combined with personalized lifestyle support including a protein-rich diet, hydration, exercise, and behavior coaching.
Regular check-ins: Our providers will monitor your weight, blood pressure, and overall well-being regularly to ensure your safety and progress.
Why Choose Us?
At our clinic, phentermine is part of a comprehensive, medically supervised program designed to help you achieve real, lasting results. You’ll get expert guidance, ongoing support, and a full plan that prioritizes your health—not just the number on the scale.
Get Your Kentucky Medical Cannabis Card


Medical cannabis has become a legal and regulated treatment option in Kentucky as of January 1, 2025, under Senate Bill 47, signed into law in March 2023. This legislation allows qualified patients with specific medical conditions to access cannabis-based therapies under the supervision of licensed healthcare providers. Call or email to schedule an appointment to speak with one of our certified providers today.
Who Qualifies for Medical Cannabis?
To be eligible for Kentucky’s medical cannabis program, you must:
Be a Kentucky resident.
Be diagnosed with a qualifying medical condition.
Minors can also qualify for a cannabis card with parental or guardian permission. This reflects the states commitment to ensuring medical cannabis access for all ages, including young individuals who may benefit from this form of treatment.
Approved conditions include (but may not be limited to):
Cancer
Chronic or severe pain
Epilepsy and other seizure disorders
Multiple sclerosis (MS)
Post-traumatic stress disorder (PTSD)
Nausea or vomiting related to chronic illness or treatment
The list of qualifying conditions may expand as the program develops.
How to Get Certified
Schedule an appointment with a medical provider who is registered with the state’s medical cannabis program.
Your provider will assess your medical history and condition.
If appropriate, you will receive a written certification for medical cannabis use.
You can then apply for a Kentucky Medical Cannabis Card through the Cabinet for Health and Family Services and can expect approval within 30 days of applying.
Approved Forms of Medical Cannabis
Under Kentucky law, smoking cannabis is not permitted. The following forms will be allowed:
Oils and tinctures
Capsules and tablets
Edibles
Vaporizable products (non-smokable)
Your healthcare provider will help determine the most appropriate form for your condition.
Where to Access Medical Cannabis
Beginning in 2025, certified patients may purchase medical cannabis products from state-licensed dispensaries located throughout Kentucky. Only licensed facilities are legally allowed to sell cannabis products under this program.
Legal Protections and Restrictions
Patients and caregivers who are certified and in compliance with Kentucky’s medical cannabis laws will be protected from prosecution under state law.
Driving under the influence of cannabis is strictly prohibited.
Federal law still classifies cannabis as a controlled substance, so possession may be illegal on federal property and cannot be transported across state lines.
Stay Informed
The Kentucky Cabinet for Health and Family Services is responsible for developing the rules and procedures for the medical cannabis program, including dispensary licensing and product safety standards.
We encourage patients to:
Stay updated through official state resources.
Talk with a licensed healthcare provider about your eligibility and treatment options.
Follow all state guidelines to remain in compliance.
PRP Treatments in Hopkinsville, KY | Natural Skin & Body Rejuvenation
Experience Natural Beauty Enhancement with PRP Therapy in Hopkinsville, Kentucky
Looking for a natural, non-surgical way to rejuvenate your face, enhance your lips, or restore thinning hair? At our Hopkinsville clinic, we offer Platelet-Rich Plasma (PRP) treatments that use your body’s own healing power to improve skin tone, boost collagen, and support tissue regeneration.
🌿 What Is PRP (Platelet-Rich Plasma) Therapy?
PRP is made from your own blood. After a quick blood draw, we separate the platelet-rich plasma in a centrifuge. This PRP is then carefully injected into targeted areas to stimulate natural healing, collagen production, and skin rejuvenation.
💉 PRP Aesthetic Treatments Available in Hopkinsville, KY
PRP Facial ("Vampire Facial")
A popular choice for patients in Hopkinsville seeking a refreshed look without surgery. This treatment uses PRP to reduce fine lines, tighten skin, and even out tone—often combined with microneedling for deeper penetration.
PRP Lip Rejuvenation
If you're looking for a natural alternative to lip fillers in Hopkinsville, PRP lip injections enhance softness, hydration, and volume without artificial substances. Ideal for a subtle, natural-looking result.
PRP Breast Enhancement ("Vampire Breast Lift")
Our non-surgical PRP breast lift is designed to gently lift and improve the skin texture around the cleavage. While it doesn’t replace surgical options, it offers a mild enhancement with no downtime.
PRP for Buttocks
Enhance the appearance of the skin on your buttocks with PRP injections. Patients in the Hopkinsville area choose this for improved skin tone and firmness without surgery.
PRP for Hair Loss
Our PRP hair restoration treatments can help stimulate new hair growth in thinning areas. We provide safe, minimally invasive care for men and women in Hopkinsville experiencing early signs of hair loss.
✅ Why Choose PRP Therapy?
Uses your body’s own healing factors
Little to no downtime
No synthetic products or chemicals
Suitable for face, lips, scalp, breasts, and more
Safe, natural approach to cosmetic enhancement
Important Reminder
While PRP therapy has shown great promise in aesthetic medicine, it is not currently approved by the FDA for cosmetic use. All procedures are performed off-label by our trained and licensed medical team, prioritizing your safety and satisfaction.
📞 Book Your PRP Consultation in Hopkinsville Today
Ready to see what PRP therapy can do for you? Schedule a private consultation with our team to discuss your goals and create a personalized treatment plan.


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Email: Comprehensivecareclinicpllc@gmail.com
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